Clinical Research Essays (Examples)
Study Document
Stem Cell Transplants Treat Alzheimers And Parkinsons Disease
… therapy for those with Parkinson’s disease. But lifestyle changes, approved drugs, and surgical operations can be recommended to address symptoms. Nevertheless, stem cell research has shown a lot of promise in helping to restore and regenerate destroyed brain tissues and is, therefore, currently being tested to help … approach in the treatment of Alzheimer’s and Parkinson’s diseases. It also investigates the possible drawbacks of using the approach.
Introduction
Expectations from medical research to come up with a breakthrough treatment for the most widely-occurring neurodegenerative ailments in the French population, namely, Parkinson's Disease (PD) and Alzheimer's … responsible for controlling movement. The degeneration leads to lower levels of neurotransmitter, dopamine, within the patient's brain, vital to body movement regulation.
Parkinson's' clinical symptoms emerge when roughly 70 percent of neurons that produce dopamine get damaged. They include bradykinesia (or a slowing down of physical movement), … the disease impacting around one……
References
References
Alzheimer’s Association. (2015). 2015 Alzheimer\\\\'s disease facts and figures. Alzheimer\\\\'s & Dementia, 11(3), 332-384. doi:10.1016/j.jalz.2015.02.003.
Bali, P., Lahiri, D., Banik, A., Nehru, B., & Anand, A. (2017). Potential for Stem Cells Therapy in Alzheimer’s Disease: Do Neurotrophic Factors Play Critical Role? Current Alzheimer Research, 14(2), 208-220. doi:10.2174/1567205013666160314145347
Goodarzi, P., Aghayan, H. R., Larijani, B., Soleimani, M., Dehpour, A. R., Sahebjam, M., … Arjmand, B. (2015). Stem cell-based approach for the treatment of Parkinson\\\\'s disease. Medical journal of the Islamic Republic of Iran, 29, 168.
Herberts, C. A., Kwa, M. S., & Hermsen, H. P. (2011). Risk factors in the development of stem cell therapy. Journal of Translational Medicine, 9(1). doi:10.1186/1479-5876-9-29
Hwang, S., Gill, S., Pathak, S., & Subramanian, S. (2018, March 30). A Comparison of Stem Cell Therapies for Parkinson Disease | Published in Georgetown Medical Review. Retrieved June 11, 2019, from https://gmr.scholasticahq.com/article/3420-a-comparison-of-stem-cell-therapies-for-parkinson-disease
Railton, D. (2019, February 18). Stem cells: Therapy, controversy, and research. Retrieved June 11, 2019, from https://www.medicalnewstoday.com/articles/200904.php
The Research Journal. (2017, September 20). Alzheimer\\\\'s and Parkinson\\\\'s - the current state of research. Retrieved June 11, 2019, from https://www.pasteur.fr/en/research-journal/reports/alzheimer-s-and-parkinson-s-current-state-research
Study Document
Optimizing Health Information Systems
… paper is to explicate the responsibilities involved in implementing a health information system (HIS) that meets current Health Information Technology for Economic and clinical Health (HITECH) Act and the Health Insurance Portability and Accountability Act (HIPAA) Security and Privacy regulatory requirements. To this end, a discussion and … for evaluating the success of the implementation of a system by incorporating two professional organization standards are followed by a summary of the research and important findings about the challenges and issues involved are presented in the paper’s conclusion..
A. Discussion and analysis of health information systems
… by Abouzhar (2009) as an "integrated effort to collect, process, report and use health information and knowledge to influence policy-making, program action and research" (p. 578). Although health information systems may differ significantly in terms of configurations and capabilities, they typically share some common features that are … well-being assessments
? Personalized interventions……
References
References
Abouzhar, C. & Boerma, T. (2009, August). Health information systems: The foundations of public health. Bulletin of the World Health Organization, 83(8), 578-583.
Cresswell, K. & Aziz, S. (2013, May). Organizational issues in the implementation and adoption of health information technology innovations: An interpretative review. International Journal of Medical Informatics, 87(5), 73-86.
Drazen, E. L. (2006, February). Maximizing the benefits of health care information systems. Journal of Medical Systems, 10(1), 51-56.
Kruse, C. S. & Smith, D. (2017, July). Security techniques for the electronic health records. Journal of Medical Systems, 41(8), 127.
Kumar, V. (2011). Impact of health information systems on organizational health communication and behavior. The Internet Journal of Allied Health Sciences and Practice, 9(2), 37-44.
McGrail, K. M. & Black, C. (2009, August). Access to data in health information systems. Bulletin of the World Health Organization, 83(8), 563-569.
Murphy, M. L. (2019, March). Mastering accounting for business combinations: Mergers and acquisitions present challenges that finance can overcome by staying involved with the deal and preparing in advance of the closing. Journal of Accountancy, 227(3), 24-27.
NAHQ code of ethics for healthcare quality. (2019). National Association for Healthcare Quality. Retrieved from https://nahq.org/about/code-of-ethics .
Study Document
Transgender The Behaviors Acts And Transitions
… individual's gender identity or expression is conflicting with their assigned sex traits and characteristics. More often than not, gender incongruence is supplemented by clinical pertinent psychological anguish, also referred to as gender dysphoria. People with gender incongruence are termed as trans persons. This terminology encompasses individuals whose … and surgical interventions can relieve gender dysphoria (Jellestad et al., 2018). Weinforth et al. (2019) indicate that if persons with gender incongruence develop clinical relevant biopsychological anguish and suffering in-line with the DSM-5 classification; it implies that physical transitioning is the ideal option for transgender people for … alleviating gender dysphoria symptoms. In this setting, gender reassignment, surgery, and hormonal treatment play a pivotal role.
Substance Abuse and relation to transgender
research has indicated that there is a high prevalence of substance abuse amongst transgender people. clinical studies have demonstrated that high percentages of substance abuse are accredited to individuals facing……
References
References
Bockting, W. O., Miner, M. H., Swinburne Romine, R. E., Hamilton, A., & Coleman, E. (2013). Stigma, mental health, and resilience in an online sample of the US transgender population. American journal of public health, 103(5), 943-951.
Bockting, W., Coleman, E., Deutsch, M. B., Guillamon, A., Meyer, I., Meyer III, W., ... & Ettner, R. (2016). Adult development and quality of life of transgender and gender-nonconforming people. Current opinion in endocrinology, diabetes, and obesity, 23(2), 188.
Catelan, R. F., Costa, A. B., & Lisboa, C. S. D. M. (2017). Psychological interventions for transgender persons: a scoping review. International Journal of Sexual Health, 29(4), 325-337.
Divan, V., Cortez, C., Smelyanskaya, M., & Keatley, J. (2016). Transgender social inclusion and equality: a pivotal path to development. Journal of the International AIDS Society, 19, 20803.
Drydakis, N. (2020). Trans People, Transitioning, Mental Health, Life, and Job Satisfaction. Handbook of Labor, Human Resources and Population Economics, 1-22.
Glynn, T. R., & van den Berg, J. J. (2017). A systematic review of interventions to reduce problematic substance use among transgender individuals: A call to action. Transgender Health, 2(1), 45-59.
Grossman, A. H., Haney, A. P., Edwards, P., Alessi, E. J., Ardon, M., & Howell, T. J. (2009). Lesbian, gay, bisexual, and transgender youth talk about experiencing and coping with school violence: A qualitative study. Journal of LGBT Youth, 6(1), 24-46.
Jellestad, L., Jäggi, T., Corbisiero, S., Schaefer, D. J., Jenewein, J., Schneeberger, A., ... & Garcia Nuñez, D. (2018). Quality of life in transitioned trans persons: a retrospective cross-sectional cohort study. BioMed research international, 2018.
Study Document
Governments Procurement Methods In Integrated Public Service
… are conflicting views regarding the process of negotiation, participation by the public and private financiers, and accountability. In recent days, a lot of research has been focusing on the implementation of PPPs. The Public-Private Partnership programs have been put to use in both developed and developing countries.
… and many have been adopted or tried. There are also case studies that have been widely used elsewhere. These initiatives have stimulated further research in PPPs. The result has been the development of new PPP models, frameworks, issues to do with concession, project financing, risk management, allocation, … While there have been numerous efforts to streamline PPPs, efforts to streamline their framework have been random.
Further, the development trends of PPP research are still unclear. There has been some research to establish the trends by analysis of the content of popular construction magazines, but the research still have little to show……
References
Bibliography
Duff, V. (2020). What is organizational integration? Retrieved from https://smallbusiness.chron.com/organizational-integration-82053.html
Friedman, S. (2016). Successful public/private partnerships from principles to practices. Washington, DC: Urban Land Institute.
Ma, L., Li, J., Jin, R., &Ke, Y. (2019). A holistic review of public-private partnership literature published between 2008 and 2018. Advances in Civil Engineering. Retrieved from http://downloads.hindawi.com/journals/ace/2019/7094653.pdf
PrivacySense. (2016). Public sector. Retrieved from http://www.privacysense.net/terms/public-sector/
Reddy, C. (2016). Staff training: Importance, benefits, advantages, and disadvantages. Retrieved from https://content.wisestep.com/staff-training-importance-benefits-advantages-disadvantages/
Sekhri, N., Feachem, R., & Ni, A. (2011). Public-private integrated partnerships demonstrate the potential to improve health care access, quality, and efficiency. Health Affairs, 30(8).
Study Document
Right Of Informed Refusal For Minors
… to examine the arguments in support of and against allow minors to make end-of-life decisions for themselves, followed by a summary of the research and important findings concerning this issue in the conclusion.
Review and Analysis
On the one hand, there are increasing calls to allow young … practice is unique in that developmental maturation allows, over time, for increasing inclusion of the child’s and adolescent’s opinion in medical decision-making in clinical practice and research” (2016, p. 30). This observation suggests that the ability of minors to participate in their health care decisions exists along a continuum ranging … status, though, essentially ends when it comes to providing minors with the same right to informed consent and informed refusal as adults. The research was consistent in showing that this view is gradually changing, due in large part……
References
References
Black’s law dictionary. (1990). St. Paul, MN: West Publishing Company.
Bryden, J. (2016, February 25). Medical help in dying should be widely available, with few restrictions: Report. The Canadian Press, 6.
Hursthouse, R. & Pettigrove, G. (2018, Winter). Virtue ethics. The Stanford Encyclopedia of Philosophy. Retrieved from https://plato.stanford.edu/archives/win2018/entries/ethics-virtue .
Katz, A. L. & Webb, S. A. (2016, August). Informed consent in decision-making in pediatric practice. Pediatrics, 138(2), 30-37.
Lemmens, C. (2009, September). End- of- life decisions and minors: do minors have the right to refuse life preserving medical treatment? A comparative study. Medical Law Review, 28(3), 479-497.
Physician-assisted suicide. (2019). CNN. Retrieved from https://www.cnn.com/2014/11/26/us/ physician-assisted-suicide-fast-facts/index.html.
Salsberry, P. J. (1999, January 1). Caring, virtue theory, and a foundation for nursing ethics. Scholarly Inquiry for Nursing Practice, 6(2), 155-160.
Williams, Z. (2012, October 25). Early puberty: why are kids growing up faster? The Guardian. Retrieved from https://www.theguardian.com/society/2012/oct/25/early-puberty-growing-up-faster .
Study Document
Huntington Disease Involving Oral Histology And Embryology
… can be postulated to slow down the onset and progression of the disease.
Conclusion
Currently there is no cure for Huntington’s disease. Medical research are consistently working on potential solutions for delaying the activation or targeting the replication of the aberrant gene. However, possible solutions to the ……
References
References
Boyle, C. A., Frölander, C., & Manley, G. (2008). Providing Dental Care for Patients with Huntington’s Disease. Dental Update, 35(5), 333–336. doi:10.12968/denu.2008.35.5.333. Retrieved from: https://sci-hub.tw/https://doi.org/10.12968/denu.2008.35.5.333
Hergert, D. C., Sanchez-Ramos, J., & Cimino, C. R. (2019). Awareness of Chorea in Huntington’s Disease. Journal of Huntington’s Disease, 1–5. doi:10.3233/jhd-190381. Retrieved from: https://sci-hub.tw/10.3233/JHD-190381
Manley, G., Lane, H., Carlsson, A., Ahlborg, B., Mårtensson, Å., Nilsson, M. B., … Rae, D. (2012). Guideline for oral healthcare of adults with Huntington’s disease. Neurodegenerative Disease Management, 2(1), 55–65. doi:10.2217/nmt.11.68. Retrieved from: https://sci-hub.tw/https://doi.org/10.2217/nmt.11.68
McColgan, P., & Tabrizi, S. J. (2017). Huntington’s disease: a clinical review. European Journal of Neurology, 25(1), 24–34. doi:10.1111/ene.13413. Retrieved from: https://sci-hub.tw/https://doi.org/10.1111/ene.13413
Petersén, Å., & Weydt, P. (2019). The psychopharmacology of Huntington disease. Handbook of Clinical Neurology, 165(3), 179–189. doi:10.1016/b978-0-444-64012-3.00010-1. Retrieved from: https://sci-hub.tw/10.1016/B978-0-444-64012-3.00010-1
Rodríguez, M. L, Sánchez, V. E. (2015). Periodontitis determining the onset and progression of Huntington\\\\\\'s disease: review of the literature. Medwave, 15(9). doi:10.5867/medwave.2015.09.6293.
Roos, R. A. C. (2010). Huntington’s disease: a clinical review. Orphanet Journal of Rare Diseases, 5(1), pp.40-48. doi:10.1186/1750-1172-5-40. Retrieved from: https://sci-hub.tw/https://dx.doi.org/10.1186%2F1750-1172-5-40
Saft, C., Andrich, J. E., Müller, T., Becker, J., & Jackowski, J. (2013). Oral and dental health in Huntington‘s disease - an observational study. BMC Neurology, 13(1), 2-5. doi:10.1186/1471-2377-13-114. Retrieved from: https://sci-hub.tw/https://dx.doi.org/10.1186%2F1471-2377-13-114
Study Document
Impact Of Phobias
… situation.
· The anxiety, fear, or avoidance is persistent and typically lasts 6 months or more.
· The anxiety, fear, or avoidance causes clinical significant distress or impairment in occupational, social, or other vital areas of functioning.
· The disturbance cannot be better explained by symptoms of ……
References
References
Campos, D., Mira, A., Bretón-López, J., Castilla, D., Botella, C., Baños, R. M., & Quero, S. (2018). The acceptability of an internet-based exposure treatment for flying phobia with and without therapist guidance: patients’ expectations, satisfaction, treatment preferences, and usability. Neuropsychiatric disease and treatment, 14, 879.
Carleton, R. N., Thibodeau, M. A., Weeks, J. W., Teale Sapach, M. J. N., McEvoy, P. M., Horswill, S. C., & Heimberg, R. G. (2014). Comparing short forms of the Social Interaction Anxiety Scale and the Social Phobia Scale. Psychological assessment, 26(4), 1116-1126. doi:10.1037/a0037063
Erceg-Hurn, D. M., & McEvoy, P. M. (2018). Bigger is better: Full-length versions of the Social Interaction Anxiety Scale and Social Phobia Scale outperform short forms at assessing treatment outcome. Psychological assessment, 30(11), 1512-1526. doi:10.1037/pas0000601
Goetter, E. M., Frumkin, M. R., Palitz, S. A., Swee, M. B., Baker, A. W., Bui, E., & Simon, N. M. (2018). Barriers to mental health treatment among individuals with social anxiety disorder and generalized anxiety disorder. Psychological Services, No Pagination Specified-No Pagination Specified. doi:10.1037/ser0000254
Halldorsdottir, T., & Ollendick, T. H. (2016). Long-term outcomes of brief, intensive CBT for specific phobias: The negative impact of ADHD symptoms. Journal of Consulting and Clinical Psychology, 84(5), 465-471. doi:10.1037/ccp0000088
Hirsch, J. A. (2018). Integrating Hypnosis with Other Therapies for Treating Specific Phobias: A Case Series. American Journal of Clinical Hypnosis, 60(4), 367-377.
Leitenberg, H., Agras, W. S., Barlow, D. H., & Oliveau, D. C. (1969). Contribution of selective positive reinforcement and therapeutic instructions to systematic desensitization therapy. Journal of Abnormal Psychology, 74(1), 113-118. doi:10.1037/h0027063
Probst, T., Berger, T., Meyer, B., Späth, C., Schröder, J., Hohagen, F., . . . Klein, J. P. (2019). Social phobia moderates the outcome in the EVIDENT study: A randomized controlled trial on an Internet-based psychological intervention for mild to moderate depressive symptoms [Press release]
Study Document
Raising Families In The 1950s After World War II
Usual Roles for Men and Women Raising Families in the 1950s after World War II
Background of research generation or individual, historical and present
The 1950s epoch is often perceived as an era of conformity, during which both genders adhered to … in rural regions, are amongst the reasons why the older individuals feel that their quality of life may be better in rural expanses. research studies conducted by various scholars have demonstrated that physical health is worse amongst the rural population as compared to the population in the ……
References
References
Baernholdt, M., Yan, G., Hinton, I., Rose, K., & Mattos, M. (2012). Quality of life in rural and urban adults 65 years and older: findings from the National Health and Nutrition Examination survey. The Journal of Rural Health, 28(4), 339-347.
Canizares, M., Gignac, M., Hogg-Johnson, S., Glazier, R. H., & Badley, E. M. (2016). Do baby boomers use more healthcare services than other generations? Longitudinal trajectories of physician service use across five birth cohorts. BMJ Open, 6(9), e013276.
Cleary, K. K., & Howell, D. M. (2006). Using the SF-36 to determine perceived health-related quality of life in rural Idaho seniors. Journal of allied health, 35(3), 156-161.
Hall, R. C., Hall, R. C., & Chapman, M. J. (2003). Identifying geriatric patients at risk for suicide and depression. Clinical Geriatrics, 11, 36-44.
Khan Academy. (2020). Women in the 1950s: Learn about the myths and realities of women\\\\\\\\\\\\'s lives during the 1950s. Retrieved 8 March 2020 from https://www.khanacademy.org/humanities/us-history/postwarera/1950s-america/a/women-in-the-1950s
Oguzturk, O. (2008). Differences in quality of life in rural and urban populations. Clinical and investigative medicine, E346-E350.
Phillipson, C., Leach, R., Money, A., & Biggs, S. (2008). Social and cultural constructions of aging: the case of the baby boomers. Sociological Research Online, 13(3), 1-14.
Rinfrette, E. S. (2009). Treatment of anxiety, depression, and alcohol disorders in the elderly: Social work collaboration in primary care. Journal of evidence-based social work, 6(1), 79-91.
Study Document
Healthcare Provider Shortage
… during the 2-year period. MedChi should also partner with healthcare facilities in the county to identify relevant technologies to be adopted in the clinical setting. The partnerships should incorporate identification of necessary financial resources for these healthcare settings to purchase and utilize these technologies in their clinical settings/environment. This activity will be carried out for a period ranging between 6 months to one year. The required resources for the implementation ……
References
References
Antonelli, A.F. (2019, May 14). Does America Have a Physician Shortage – or Are Our Doctors ‘Just Bad at Managing Time’? Retrieved August 5, 2019, https://www.advisory.com/daily-briefing/2019/05/14/physician-shortage
Daly, R. (2018, May 22). Healthcare Workforce Shortage Worsening: Senators. Retrieved August 5, 2019, from https://www.hfma.org/topics/news/2018/05/60811.html
Desmon, S. (2019, March 1). Doctors in Short Supply in Rural Maryland. Baltimore Sun. Retrieved August 5, 2019, from https://www.baltimoresun.com/bal-id.rural01mar01-story.html
Heath, S. (2019, July 11). What Clinician Recruitment Tactics Say About the Physician Shortage. Retrieved August 5, 2019, from https://patientengagementhit.com/news/what-clinician-recruitment-tactics-say-about-the-physician-shortage
Merritt Hawkins. (2019). 2019 Review of Physician and Advanced Practitioner Recruiting Incentives. Retrieved August 5, 2019, from https://www.merritthawkins.com/uploadedFiles/merritthawkins_2019_incentivereview.pdf
Western Maryland Health System and Allegany County Health Department. (2011, November). Allegany County Community Health Needs Assessment. Retrieved August 5, 2019, from http://www.alleganyhealthplanningcoalition.com/pdf/ACHD%20Community%20Health%20Needs%20Assessment.pdf
Wolford, H.B. (2018, May 28). Allegany County Sees Shortage of Health Care Workers. Time News. Retrieved August 5, 2019, from https://www.times-news.com/news/local_news/allegany-county-sees-shortage-of-health-care-workers/article_28b1030d-4403-5d84-aa26-fe17d61b8561.html
Study Document
The Karen Ann Quinlan Case Legal Aspects Of Healthcare
...Clinical research Facts and Court Holding
Karen Ann Quinlan attracted national attention following her slipping into a comma in 1975. In essence, the Quinlan case remains a key reference point in discussions revolving around the right to die. According to Drane (1994) Ms. Quinlan fell into a comma on the night of April 15, 1975 following her an evening birthday party of one of her friends. It was reported that during the party, Quinlan took a cocktail of alcoholic beverages. In additional to alcohol, it was also reported that she took a tranquilizer (Valium to be specific) (Drane, 1994). She promptly slid into a comma. Soon, her friends realized she was not breathing and called an ambulance which rushed her to Newton Memorial Hospital. Efforts to resuscitate Quinlan were unsuccessful and after it became apparent that her comma was irreversible, she was transferred to another medical facility, i.e. St. Clare’s in Danville.……
References
References
Drane, J.F. (1994). Clinical Bioethics: Theory and Practice in Medical Ethical Decision-making. New York, NY: Rowman & Littlefield.
Holland, S., Kitzinger, C. & Kitzinger, J. (2014). Death, treatment decisions and the permanent vegetative state: evidence from families and experts. Med Health Care Philos., 17(3), 413-423.
Karen Ann Quinlan Hospice (2019). The Story of Karen Ann Quinlan Made Headlines! Retrieved from https://www.karenannquinlanhospice.org/about/history/
Mizzoni, J. (2011). Ethics: The Basics. Hoboken, NJ: John Wiley & Sons.
Rosenthal, M.S. (2018). Clinical Ethics on Film: A Guide for Medical Educators. New York, NY: Springer.
Singer, P. (2013). A Companion to Ethics. Hoboken, NJ: John Wiley & Sons.
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